Samacbd

Glossary

Endo cannabinoid:

The endocannabinoid system (ECS) is a sophisticated cell-signaling network. Theendocannabinoid system (ECS) is a broad neuromodulatory system that performscritical functions in the development of the central nervous system (CNS). Theyoperate as traffic policeman, regulating the levels and activity of most other neurotransmitters. Endocannabinoids, also known as endogenous cannabinoids, are substances that your body produces. ECS is essential for practically every element of our day-to-day functioning. Many of our most important body processes are regulated and controlled by the ECS, including learning and memory, emotional processing, sleep, temperature management, pain control, inflammatory andimmunological responses, and feeding.

CBD:
CBD is a molecule that occurs naturally in the Cannabis sativa plant. CBD is non-intoxicating, has a variety of potential medicinal advantages, and has none of the adverse effects associated with standard pain relievers. CBD strengthens the human body’s cells and aids in their renewal. Furthermore, CBD is an antioxidant that generates a clear impact without the presence of free radicals.
TCH:
THC is the main psychoactive compound in cannabis that producesthe high sensation. THC binds with the cannabinoid 1 (CB1) receptors in the brain.It produces a high or a sense of euphoria. Its anti-emetic properties (inhibits vomiting) are particularly useful in the treatment of cancer patients on chemotherapy. Also, as THC increases the appetite and reduces the vomit response, it is starting to be used in the treatment of anorexia and other eating disorders.
Cannabis sativa:
Cannabis sativa is an important herbaceous species originating from Central Asia,which has been used in folk medicine. This fast-growing plant has recently seen aresurgence of interest because of its multi-purpose applications: it is indeed a treasure trove of phytochemicals and a rich source of both cellulosic and woody fibers. Equally highly interested in this plant are the pharmaceutical and construction sectors, since its metabolites show potent bioactivities on human health.
CB1:
The CB1 receptor is one of the most abundant G protein-coupled receptors(GPCRs) in the CNS and is found in particularly high levels in the neocortex,hippocampus, basal ganglia, cerebellum and brainstem. CB1 receptors are highly enriched at presynaptic and axonal compartments, restricting their function to sitesof synaptic activity. The CB1 receptor binds the main active ingredient of Cannabis sativa (marijuana), Δ9-tetrahydrocannabinol (Δ9-THC) and mediates most of the CNS effects of Δ9-THC . CB1 receptors exhibit constitutive activity indicative of G protein activation in the absence of agonists and this could mediate their highly polarized localization to axonal and presynaptic compartments.
CB2:
The CB2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in immune tissues, highlighting the possibility that the endocannabinoid system has an immunomodulatory role. CB2 receptor was shown to modulate immune cell functions, both in cellulo and in animal models of inflammatory diseases. CB2 receptor was postulated to be responsible for the immunomodulatory effects of cannabinoids and endocannabinoids.
Osteoarthritis:
Arthritis refers to biomechanical changes within a joint. Osteoarthritis, also known as degenerative joint disease (DJD), is the most common type of arthritis.Osteoarthritis is more likely to develop as people age. The changes inosteoarthritis usually occur slowly over many years, though there are occasional exceptions. Inflammation and injury to the joint cause bony changes, deterioration of tendons and ligaments and a breakdown of cartilage, resulting in pain, swelling, and deformity of the joint. The main symptoms of osteoarthritis are pain and sometimes stiffness in the affected joints.
Multiple sclerosis:
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent damage or deterioration of the nerve fibers. Some people have mild symptoms, such as blurred vision and numbness, and tingling in the limbs. In severe cases, a person may experience paralysis, vision loss, and mobility problems.
Eczema:
Atopic dermatitis (eczema) is a condition that causes dry, itchy and inflamed skin. It's common in young children but can occur at any age. Atopic dermatitis is long lasting (chronic) and tends to flare sometimes. It can be irritating but it's not contagious. People with atopic dermatitis are at risk of developing food allergies, hay fever and asthma. Eczema doesn’t usually cause pain. If you scratch your skin, you could break the surface of your skin and create a sore, which could be painful.
PCOS:

PCOS is a disorder in which the ovaries create an inordinate quantity of androgens,male sex hormones that are normally present in tiny levels in women. The term polycystic ovarian syndrome refers to the ovaries’ many tiny cysts (fluid-filled sacs). However, some women with this illness do not produce cysts, and some women without the disorder do. Ovulation is the release of a mature egg from an ovary. This occurs so that it can be fertilised by male sperm. If the egg is not fertilised, it is excreted during your period.

In rare situations, a woman may not produce enough of the hormones required for eovulation. When ovulation does not occur, the ovaries might generate a large number of tiny cysts. These cysts produce androgens, which are hormones. Women with PCOS frequently have elevated amounts of androgens. This can exacerbate a woman’s menstrual cycle difficulties. It can also induce many of the symptoms associated with PCOS.

Spondylitis:
Ankylosing spondylitis is an inflammatory disease that, over time, can cause some of the bones in the spine (vertebrae) to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply. Early signs and symptoms of ankylosing spondylitis might include pain and stiffness in the lower back and hips, especially in the morning and after periods of inactivity. Neck pain and fatigue also are common. Over time, symptoms might worsen, improve or stop at irregular intervals. In severe ankylosing spondylitis, new bone forms as part of the body's attempt to heal. This new bone gradually bridges the gap between vertebrae and eventually fuses sections of vertebrae. Those parts of the spine become stiff and inflexible. Fusion can also stiffen the rib cage, restricting lung capacity and function.
Huntington’s disease:

Huntington’s disease is a rare, genetic condition that involves the gradualbreakdown (degeneration) of brain nerve cells.Huntington’s disease affects aperson’s functional skills in a variety of ways, frequently resulting in mobility,thinking (cognitive), and psychological issues.

Huntington’s disease symptoms can arise at any age, although they are most common in adults in their 30s or 40s. If the disorder appears before the age of 20, it is referred to as juvenile Huntington’s disease. When Huntington’s disease occurs early, the symptoms are considerably different, and the condition may advance more quickly.

Tourette’s disease:
Tourette Syndrome (TS) is a nervous system disorder. Tourette syndrome is a condition characterised by uncontrollable repetitive motions or noises. For example, you may continuously blink your eyes, shrug your shoulders, or make strange sounds or say unpleasant phrases. Tics are uncontrollable twitches, gestures, or noises that people do frequently. People who suffer tics are unable to control their bodies. For example, a person may keep blinking repeatedly.
Schizophrenia:
Schizophrenia is a serious mental disorder in which people interpret reality abnormally. Schizophrenia may result in some combination of hallucinations, delusions, and extremely disordered thinking and behavior that impairs daily functioning, and can be disabling. Signs and symptoms may vary, but usually involve delusions, hallucinations or disorganized speech, and reflect an impaired ability to function.
VIjaya:
Ayurvedic practitioners have employed Vijaya, also known as Bhanga and cannabis, a medication of natural origin, to treat a variety of illness problems. Cannabis sativa Linn., a member of the Cannabinaceae family, is the plant's botanical source. Vijaya is well-known for its antiemetic qualities against chemotherapy-induced vomiting, glaucoma (intraocular pressure), sleeplessness, anxiety, depression, epilepsy, and pain.
Melatonin:

The presence of darkness causes the body to produce more melatonin, which tells the body to sleep. Light reduces melatonin synthesis and alerts the body to the fact that it is awake. Melatonin levels are low in some persons who have difficulty sleeping. It is considered that supplementing with melatonin may help them sleep.

Melatonin is most typically used to treat insomnia and improve sleep in variouscircumstances such as jet lag. It is also claimed to treat depression, chronic pain,dementia, and a variety of other ailments, although there is little scientific evidence to back up the majority of these claims.

 

Hemp seed oil:
Hemp seed oil is derived from hemp plant seeds. THC levels in hemp plants do not surpass 0.3%. Hemp seed oil has several health advantages due to its high level of three polyunsaturated fatty acids: linoleic acid, alpha-linolenic acid, and gamma- linolenic acid. Furthermore, its omega-6 (linoleic acid) to omega-3 (alpha-linolenic acid) fatty acid ratio is 3:1. The anti-inflammatory qualities of hemp seed oil aid with pain relief. Because of its rich omega-3 fatty acid content, hemp seed oil is an excellent supplement for pregnant women. They promote good brain and eye development in the newborn and may aid in the prevention of maternal depression.
Ylang ylang oil:
The blooms of Cananga odorata genuina are used to make ylang ylang oil. It is occasionally used in aromatherapy or used topically as medication. Ylang ylang oil is used in cosmetics and soaps as a fragrance and as a culinary flavouring. Linalool, an antifungal component found in ylang ylang oil, is one of its numerous advantages. Furthermore, ylang ylang essential oil improves health by combating microbial infections. Isoeugenol is another chemical found in ylang ylang oil. Because of its anti-inflammatory characteristics, this one decreases oxidative stress. It also has calming effects. It is also recognised to reduce the risk of cardiovascular and cancer-related diseases.
Schizophrenia:
Schizophrenia is a dangerous mental condition in which people have an aberrant interpretation of reality. Schizophrenia can include hallucinations, delusions, and profoundly disturbed thought and behaviour that interferes with everyday functioning and can be debilitating. Schizophrenia symptoms vary from person to person, although they are commonly classified as psychotic, negative, or cognitive. Schizophrenia patients must be treated for the rest of their lives.
Bipolar illness:
Bipolar disorder, formerly known as manic depression, is a mental illness characterised by significant mood fluctuations that include emotional highs (mania or hypomania) and lows (depression). You may feel gloomy or hopeless when you are depressed, and you may lose interest or pleasure in most activities. When your mood switches to mania or hypomania (a milder form of mania), you may feel ecstatic, energised, or particularly irritated.
Schizophrenia:

Schizophrenia is a dangerous mental condition in which people have an aberrant interpretation of reality. Schizophrenia can include hallucinations, delusions, and profoundly disturbed thought and behaviour that interferes with everydayfunctioning and can be debilitating. Schizophrenia symptoms vary from person to
person, although they are commonly classified as psychotic, negative, or cognitive.Schizophrenia patients must be treated for the rest of their lives.

Sleep, energy, activity, judgement, conduct, and the capacity to think clearly can all be affected by mood fluctuations. Although bipolar disorder is a chronic illness, you may control your mood swings and other symptoms by adhering to a treatment plan. Bipolar illness is often treated with medicines and psychological treatment.

Brahmi:

Brahmi is a medicinal plant that has a long history of use as a significant elementin Ayurvedic adaptogens, memory enhancers, and stress relievers.

Brahmi is a plant with small white blooms and oval leaves that is also available in the form of capsules and pills at Kerala Ayurveda. Brahmi is regarded as a brain tonic for people of all ages and genders.

Brahmi has also been shown to have therapeutic benefits against brain degeneration caused by Alzheimer’s disease. Brahmi may assist enhance endothelial function, which controls blood vessel constriction and dilation to regulate blood pressure. It also allows the body to use more nitric acid, which is good for blood pressure. Brahmi aids in the promotion of various activities by monitoring and regulating them. By managing and regulating these functions,
Brahmi helps promote normal blood pressure.

Schizophrenia:

Schizophrenia is a dangerous mental condition in which people have an aberrant interpretation of reality. Schizophrenia can include hallucinations, delusions, and profoundly disturbed thought and behaviour that interferes with everydayfunctioning and can be debilitating. Schizophrenia symptoms vary from person to
person, although they are commonly classified as psychotic, negative, or cognitive.Schizophrenia patients must be treated for the rest of their lives.

Sleep, energy, activity, judgement, conduct, and the capacity to think clearly can all be affected by mood fluctuations. Although bipolar disorder is a chronic illness, you may control your mood swings and other symptoms by adhering to a treatment plan. Bipolar illness is often treated with medicines and psychological treatment.

Parkinson’s disease:

Parkinson’s disease is a progressive ailment that affects the neurological system and the nerve-controlled areas of the body. The symptoms appear gradually. The initial sign might be a little tremor in only one hand. Although tremors areprevalent, the disease can also induce stiffness or slowness of movement.Parkinson’s disease can cause movement to slow down, making routine tasks difficult and time-consuming.

When you walk, your steps may become shorter. Getting out of a chair may be tough. As you try to walk, your feet may drag or shuffle. Muscle stiffness can happen anywhere on your body. Muscle stiffness can be uncomfortable and restrict your range of motion.

Alzheimer’s disease:
Alzheimer’s disease is a degenerative neurologic ailment that causes brain cells to die and the brain to shrink (atrophy). Alzheimer’s disease is the most prevalent form of dementia, which is defined as a progressive deterioration in cognitive, behavioural, and social abilities that impairs a person’s capacity to operate independently. The disease’s early symptoms include forgetting recent events or discussions. A person with Alzheimer’s disease will acquire significant memory impairment and lose the capacity to do daily chores as the disease develops.
Atherosclerosis:
Arteriosclerosis occurs when the blood veins (arteries) that transport oxygen and nutrients from the heart to the rest of the body thicken and stiffen, occasionally limiting blood flow to organs and tissues. Healthy arteries are elastic and flexible. However, the artery walls can harden with time, a phenomenon known as artery hardening.
Jaamansi:
Jatamansi, also known as Nardostachys jatamansi, is a tiny, rhizomatous perennial plant of the Valerianaceae family. It grows in India, China, Nepal, and Bhutan on damp, steep, rocky, undisturbed grassland slopes. The extract of jatamansi was investigated, and it was discovered to have antidepressant efficacy in the mouse model. This showed that it might help persons suffering from depression due to sleep difficulties.